Year : 2022  |  Volume : 15  |  Issue : 2  |  Page : 114--120

Transcatheter closure of congenital portosystemic shunts – A multicenter experience


Nageswara Rao Koneti1, Shweta Bakhru1, Mahimarangaiah Jayranganath2, Mahesh Kappanayil3, Prashant Bobhate4, Lakshmivenkateshiah Srinivas5, Snehal Kulkarni4, Usha Mandikal Kodandarama Sastry2, Raman Krishna Kumar3 
1 Department of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana, India
2 Department of Pediatric Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bengaluru, Karnataka, India
3 Department of Pediatric Cardiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India
4 Department of Pediatric Cardiology, Kokilaben Ambani Hospital, Mumbai, Maharashtra, India
5 Department of Pediatric Cardiology, Jupiter Hospital, Thane, Maharashtra, India

Correspondence Address:
Dr. Nageswara Rao Koneti
Department of Pediatric Cardiology, Rainbow Children's Heart Institute, Hyderabad, Telangana
India

Background: Congenital portosystemic shunts (CPSS) are rare and present variably with hepatic encephalopathy, pulmonary arteriovenous malformations (PAVMs), and pulmonary hypertension (PH). Objective: The objective of the study was to see the feasibility of transcatheter closure of CPSS and their outcome. Materials and Methods: We analyzed the data of 24 patients of CPSS who underwent transcatheter closure from five institutions (March 2013 to April 2019). Baseline evaluation included echocardiography with bubble contrast study, ultrasound examination of the abdomen, computed tomography angiogram, and cardiac catheterization with test balloon occlusion of the CPSS. The evaluation showed cyanosis due to PAVM in 12, PH in 8, and respiratory distress in 2. Two had both cyanosis and PH. Criteria for eligibility for complete catheter closure of CPSS included demonstration of intrahepatic portal vein (PV) radicals together with a PV pressure of ≤18 mmHg on occlusion. Results: The median age and weight were 8 years (0.5–21) and 19.5 kg (4.2–73), respectively. Transcatheter closure was performed in 21 patients (22 procedures) using a variety of occlusive devices and stent-graft exclusion was done in one patient. Closure was not done in 3 in view of high portal venous pressures and hypoplastic PVs. During the follow-up (median: 42 months and range: 61 days–4.8 years), saturation normalized in 14 patients with PAVM. PH declined in all eight patients who underwent the procedure. Respiratory distress improved in two patients. Conclusions: Early and short-term follow-up results of catheter closure of CPSS appear promising. However, further, follow-up is needed to demonstrate long-term effectiveness.


How to cite this article:
Koneti NR, Bakhru S, Jayranganath M, Kappanayil M, Bobhate P, Srinivas L, Kulkarni S, Kodandarama Sastry UM, Kumar RK. Transcatheter closure of congenital portosystemic shunts – A multicenter experience.Ann Pediatr Card 2022;15:114-120


How to cite this URL:
Koneti NR, Bakhru S, Jayranganath M, Kappanayil M, Bobhate P, Srinivas L, Kulkarni S, Kodandarama Sastry UM, Kumar RK. Transcatheter closure of congenital portosystemic shunts – A multicenter experience. Ann Pediatr Card [serial online] 2022 [cited 2022 Sep 25 ];15:114-120
Available from: https://www.annalspc.com/article.asp?issn=0974-2069;year=2022;volume=15;issue=2;spage=114;epage=120;aulast=Koneti;type=0