Next article Search Articles Instructions for authors  Access Statistics | Citation Manager  
FELLOW'S CORNER  

 Article Access Statistics
    Viewed734    
    Printed22    
    Emailed0    
    PDF Downloaded93    
    Comments [Add]    

Recommend this journal

Hyperviscosity syndrome revisited


1 Department of Pediatric Cardiology, Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, West Bengal, India
2 Department of Pediatric Cardiology, Pediatric Intensive Care, Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, West Bengal, India
3 Department of Pediatric Cardiology, Narayana Superspecialty Hospital, Howrah, West Bengal, India

Correspondence Address:
Dr. Debasree Gangopadhyay
Department of Pediatric Cardiology, Rabindranath Tagore International Institute of Cardiac Sciences, Mukundapur, Kolkata - 700 099, West Bengal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/apc.apc_157_21

Rights and Permissions

Year : 2022  |  Volume : 15  |  Issue : 3  |  Page : 284-290

 

SEARCH
Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles

  Article in PDF (895 KB)
Email article
Print Article
Add to My List
Secondary erythrocytosis occurs in cyanotic heart disease as a physiological response to chronic hypoxia, and this leads to hyperviscosity and various complications of the same. Microvascular stasis due to hyperviscosity results in symptoms including headache, fatigue, paraesthesia, and loss of vision. An important and dreadful feature of hyperviscosity is overt thrombosis in organ systems, resulting in cerebrovascular accident and myocardial infarction. Limited body iron store in a state of secondary erythrocytosis brings forth iron-deficient microcytic red cells; these being more rigid and less deformable than normocytic cells, further aggravate vascular occlusion. The management of hyperviscosity syndrome starts with intravenous hydration and correction of latent iron deficiency. However, therapeutic phlebotomy may be employed as a rescue measure if symptoms persist despite correction of dehydration and anemia. We present a series of four patients with uncorrected cyanotic congenital heart disease who presented with a spectrum of features of hyperviscosity and discuss pathophysiology, clinical features, and management of hyperviscosity in detail.






[FULL TEXT] [PDF]*
 

 

 

 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 
 
 Reader Comments
 Email Alert *
  *
 * Requires registration (Free)
 
 FELLOW'S CORNER
 




1 Department of Pediatric Cardiology, Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, West Bengal, India
2 Department of Pediatric Cardiology, Pediatric Intensive Care, Rabindranath Tagore International Institute of Cardiac Sciences, Kolkata, West Bengal, India
3 Department of Pediatric Cardiology, Narayana Superspecialty Hospital, Howrah, West Bengal, India

Correspondence Address:
Dr. Debasree Gangopadhyay
Department of Pediatric Cardiology, Rabindranath Tagore International Institute of Cardiac Sciences, Mukundapur, Kolkata - 700 099, West Bengal
India
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/apc.apc_157_21

Rights and Permissions

Secondary erythrocytosis occurs in cyanotic heart disease as a physiological response to chronic hypoxia, and this leads to hyperviscosity and various complications of the same. Microvascular stasis due to hyperviscosity results in symptoms including headache, fatigue, paraesthesia, and loss of vision. An important and dreadful feature of hyperviscosity is overt thrombosis in organ systems, resulting in cerebrovascular accident and myocardial infarction. Limited body iron store in a state of secondary erythrocytosis brings forth iron-deficient microcytic red cells; these being more rigid and less deformable than normocytic cells, further aggravate vascular occlusion. The management of hyperviscosity syndrome starts with intravenous hydration and correction of latent iron deficiency. However, therapeutic phlebotomy may be employed as a rescue measure if symptoms persist despite correction of dehydration and anemia. We present a series of four patients with uncorrected cyanotic congenital heart disease who presented with a spectrum of features of hyperviscosity and discuss pathophysiology, clinical features, and management of hyperviscosity in detail.






[FULL TEXT] [PDF]*


        
Print this article     Email this article